• analysis

    You are working with HPLC for the separation and identification of analytical substances in laboratories. Challenge the selectivity of Kromasil for your most sensitive analysis.

  • development

    You need to quickly purify substances for further studies in the development of pharmaceuticals. Kromasil will help you achieve your goals with ease and efficiency.

  • production

    You are using preparative chromatography for high efficiency purification in a pilot or up to industrial-scale production. The robustness of Kromasil is available in ton quantities to meet your process demands.

Application Guide

Pindolol

Separation of pindolol on Kromasil CelluCoat RP

pindolol chromatogram

Conditions

Column:Kromasil Chiral, 3 μm, CelluCoat RP, 4.6 × 150 mm
Eluent:Acetonitrile/Water, 100 mM Potassium hexafluorophosphate (40/60)
Flow rate:0.5 ml/min
Temperature:22°C
Detection:UV 254 nm

Results

k’1:0.74
N1:74347
α:2.24
Rs:8.87

Reference

Eka application note

Kromasil product availability

Availability of Kromasil Chiral, CelluCoat RP in columns
Column sizes, mm:
Particle
size, μm		4.6
×
50		4.6
×
150		4.6
×
250
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AkzoNobel, Separation Products · SE–445 80 Bohus, Sweden · Phone +46 31 58 70 00 · Fax +46 31 58 77 27 · E-mail: kromasil@akzonobel.com