Works all the way
With particle sizes from 3 μm to 10 μm giving identical selectivity, Kromasil AmyCoat makes it
easy to scale up while retaining excellent performance.
As for all Kromasil products, you can perform the required method development in
analytical-scale columns and then scale up to a larger column. You can, for example, use 3 μm
particles in an analytical scale column and translate all the generated data to a larger column
packed with 10 μm particles.
If you plan to scale up the process, we suggest you use an analytical column packed with 10
μm particles right from the start.
Example of a scale-up from analytical to 50 mm DAC prep system.
Mechanical strength is an important product lifetime parameter. Kromasil AmyCoat has a mechanically strong spherical silica which withstands repeated cycles of packing.
We manufacture the super wide pore silica for Kromasil polysaccharide products and perform all subsequent steps leading to the final product. This means you get a product with full traceability. Every manufacturing step is ensured through our detailed quality system, and the final product is never released until it has passed our rigorous quality control tests. Having all the manufacturing steps in-house also gives us a strong position in terms of production capacity.