Kromasil AmyCoat

AmyCoat

analysis

You are working with HPLC for the separation and identification of analytical substances in laboratories. Challenge the selectivity of Kromasil for your most sensitive analysis.

development

You need to quickly purify substances for further studies in the development of pharmaceuticals. Kromasil will help you achieve your goals with ease and efficiency.

You are using preparative chromatography for high efficiency purification in a pilot or up to industrial-scale production. The robustness of Kromasil is available in ton quantities to meet your process demands.

Stable performance

No pressure limits — freedom to switch solvents

No pressure limits

User-friendliness, as we see it, is the ability to perform method development without being restricted by various parameters. One well-known restriction for coated polysaccharide phases is the general pressure limit over the bed. Kromasil AmyCoat withstands flow rates generating back-pressure drops up to 400 bar — which is about the limit for most HPLC systems. This makes it possible to run analytical chromatography a lot faster.

Stable performance

From a stability perspective, you can run Kromasil AmyCoat using compatible normal, polar organic mobile phases. Switching between these mobile phases will not lead to any degradation in performance. In other words: no need for solvent-dedicated columns.

In order to test the stability of the phase the chromatographic performance was evaluated before and after a test sequence mixing high flow rate conditions and mobile phase switches (according to the table).
As shown in the figure below, the column efficiency was maintained even after the harsh conditions of the sequence.

· Eka Chemicals, Separation Products · SE–445 80 Bohus, Sweden · Phone +46 31 58 70 00 · Fax +46 31 58 77 27 ·
· E-mail kromasil@eka.com ·