Analysis

Superior separations for critical results

The importance of clear and accurate results

No matter if a project involves the development of new pharmaceutical substances, research in substances or quality control of a production batch - the results of clinical tests using HPLC dictate the success of the project. There are many factors that can affect the success or failure of a project, such as impurities in substances through contamination, poor calibration and wear and tear of equipment, inadequately developed method and so on.

However, the single most important factor that can affect success rate is achieving clear and accurate chromatography results in the laboratory. So you need silica that offers superior separation with narrow and symmetric peaks, eliminating any uncertainties.

Expect a silica that does the job

To achieve good results, batch to batch reproducibility is of the highest importance for laboratory technicians. Once a test is set up, minimal unplanned deviations in results are looked for. A validated analytical method must be based on a column/phase that shows identical performance between batches but also between columns.

The manufacturer of the silica must have a production process that can produce and validate the silica and guarantees reproducibility.

The challenge of choosing the right one

There are many suppliers of HPLC silica on the market. Unfortunately, many of their products are of inferior quality. A poorly shaped particle undoubtedly leads to lower mechanical stability. The ideal packing, of course, consists of perfectly spherical particles. This gives the highest possible mechanical stability, to maximize loadability, and excellent surface properties, to make it easier to run difficult substances.

In other words, use a silica that consists of perfectly spherical particles, is guaranteed to offer reproducibility and gives you clear and accurate results.