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Kromasil® EternityShell columns are a further expansion of the Kromasil® analytical portfolio. Kromasil® EternityShell columns have been designed for users who expect to perform separations between pH 1 and 12 and look for fast separations using solid-core technology.

Kromasil® EternityShell columns

The Kromasil® EternityShell columns are based on solid-core particles and used in the analysis of pharmaceutical, clinical, environmental, food and beverage and industrial samples.

These new columns are packed with 2.5 μm solid-core particles. Kromasil® EternityShell are aimed for fast separations similarly to the already existent Kromasil® EternityXT columns with 1.8 and 2.5 μm particles.

Illustration of a splitted solid-core particle

Extended pH range

The Kromasil® EternityShell C18 columns are robust and stable beyond traditional silica columns. Offering excellent pH flexibility between pH 1 and 12, These EternityShell columns are for users that need to work under an almost full pH range, including acidic conditions but also at tougher high pH for the analysis for bases. The new chromatographic material is endcapped, has a surface area of 110 m2/g and a carbon coverage of 8%, providing a first rate alternative selectivity for reversed phase chromatography.

pH range
Work with confidence in a pH range between 1 and 12.

More choices for analysis

Users can now choose from both fully porous and solid-core Kromasil® small particle columns to achieve their results. Here the user exploits differences in retention according to the stationary phase characteristics with maintained selectivity. Considering Kromasil® EternityShell and EternityXT, with a lower ratio of porous material available for the first one, the interaction between the compounds and the stationary phase is lower, resulting in a quicker elution. When considering Kromasil® ClassicShell and EternityShell chromatographic results, the characteristics of each stationary phase combined with the given substances allows the user to tune in the retention time.

Separation of Steroids on 3 C18 phases
In this separation of steroids, the same analysis is carried out on three C18 columns from different Kromasil® families.
  • Conditions
  • Columns: Kromasil EternityShell-2.5-C18 2.1 x 50 mm
  •   Kromasil ClassicShell-2.5-C18 2.1 x 50 mm
  •   Kromasil EternityXT-2.5-C18 2.1 x 50 mm
  • Mobile phase: acetonitrile / water
  • Gradient: 0 min: 35%, 1.5 min: 60% acetonitrile
  • Substances: 1 = cortisone, 2 = corticosterone, 3 = deoxycorticosterone
  • Flow rate: 0.6 ml/min
  • Temperature: ambient
  • Detection: UV @ 254 nm

Applications

Fast separations under harsh conditions

Separation of local anesthetics
Separation of local anesthetics.
  • Conditions
  • Column:Kromasil EternityShell-2.5-C18 2.1 x 50 mmm
  • Mobile phase:acetonitrile / water, 10 mM ammonium carbonate, pH 10.5
  • Gradient: 0 min: 30%, 1.5 min: 90% acetonitrile
  • Flow rate:0.7 ml/min
  • Temperature:ambient
  • Detection:UV @ 220 nm
  • Sample:1 = benzocaine, 2 = lidocaine,
  •  3 = tetracaine, 4 = bupivacaine
Separation of tricyclic drugs
Separation of tricyclic drugs.
  • Conditions
  • Column:Kromasil EternityShell-2.5-C18 2.1 x 50 mmm
  • Mobile phase:acetonitrile / water + 0.1% DEA
  • Gradient: 0 min: 60%, 1.5 min: 80% acetonitrile
  • Flow rate:0.6 ml/min
  • Temperature:ambient
  • Detection:UV @ 254 nm
  • Sample:1 = carbamazepine, 2 = nortriptyline,
  •  3 = imipramine, 4 = amitriptyline
Separation of aromatics
Separation of aromatics
  • Conditions
  • Column:Kromasil EternityShell-2.5-C18 2.1 x 50 mmm
  • Mobile phase:acetonitrile / water
  • Gradient: 0 min: 60%, 2 min: 85% acetonitrile
  • Flow rate:0.6 ml/min
  • Temperature:ambient
  • Detection:UV @ 254 nm
  • Sample:1 = toluene, 2 = naphthalene, 3 = biphenyl,
  •   4 = acenaphthene, 5 = phenanthrene,
  •   6 = anthracene, 7 = o-terphenyl
  •   8 = trihenylene

Availability

Availability of Kromasil® EternityShell columns

Kromasil® EternityShell is based on 2.5 μm solid-core particles, and is available with C18 derivatization, in 2.1 mm I.D. HPLC columns with lenght 50 mm and 100 mm.

Columns and box
Availability for Kromasil® columns Click/touch the dot for the combination of stationary phase and column diameter of your interest to access column length availability and further options.
Column diameters, [mm]
FamilyPhasedp [μm]2.13.03.94.04.6102021.23050
60 ÅSIL5 S05SID__ S05SIC__ S05SIB__ S05SIA__ S05SIP__ S05SIO__ S05SIR__ S05SIT__
60 ÅSIL7 S07SIB__ S07SIA__ S07SIP__ S07SIO__ S07SIR__ S07SIT__
60 ÅSIL10 S10SIB__ S10SIA__ S10SIP__ S10SIO__ S10SIR__ S10SIT__
60 ÅSIL13 S13SIB__ S13SIA__ S13SIP__ S13SIO__ S13SIR__ S13SIT__
60 ÅSIL16 S16SIB__ S16SIA__ S16SIP__ S16SIO__ S16SIR__ S16SIT__
60 ÅCN5 S05CND__ S05CNC__ S05CNJ__ S05CNB__ S05CNA__ S05CNP__ S05CNO__ S05CNR__ S05CNT__
60 ÅCN10 S10CNJ__ S10CNB__ S10CNA__ S10CNP__ S10CNO__ S10CNR__ S10CNT__
60 ÅDiol5 S05DID__ S05DIC__ S05DIB__ S05DIA__ S05DIP__ S05DIO__ S05DIR__ S05DIT__
60 ÅDiol10 S10DIB__ S10DIA__ S10DIP__ S10DIO__ S10DIR__ S10DIT__
60 ÅHILIC-D5 S05HDD__ S05HDC__ S05HDB__ S05HDA__ S05HDP__ S05HDO__ S05HDR__ S05HDT__
60 ÅHILIC-D10 S10HDB__ S10HDA__ S10HDP__ S10HDO__ S10HDR__ S10HDT__
100 ÅSIL3.5 MH3SID__ MH3SIC__ MH3SIB__ MH3SIA__ MH3SIP__
100 ÅSIL5 M05SID__ M05SIC__ M05SIJ__ M05SIB__ M05SIA__ M05SIP__ M05SIO__ M05SIR__ M05SIT__
100 ÅSIL7 M07SIB__ M07SIA__ M07SIP__ M07SIO__ M07SIR__ M07SIT__
100 ÅSIL10 M10SIJ__ M10SIB__ M10SIA__ M10SIP__ M10SIO__ M10SIR__ M10SIT__
100 ÅSIL13 M13SIB__ M13SIA__ M13SIP__ M13SIO__ M13SIR__ M13SIT__
100 ÅSIL16 M16SIB__ M16SIA__ M16SIP__ M16SIO__ M16SIR__ M16SIT__
100 ÅC15 M05C1A__
100 ÅC41.8 MF1CSD__ MF1CSC__
100 ÅC42.5 MH2CSD__ MH2CSC__ MH2CSA__
100 ÅC43.5 MH3CSD__ MH3CSC__ MH3CSB__ MH3CSA__ MH3CSP__
100 ÅC45 M05CSD__ M05CSC__ M05CSJ__ M05CSB__ M05CSA__ M05CSP__ M05CSO__ M05CSR__ M05CST__
100 ÅC47 M07CSB__ M07CSA__ M07CSP__ M07CSO__ M07CSR__ M07CST__
100 ÅC410 M10CSD__ M10CSC__ M10CSJ__ M10CSB__ M10CSA__ M10CSP__ M10CSO__ M10CSR__ M10CST__
100 ÅC413 M13CSB__ M13CSA__ M13CSP__ M13CSO__ M13CSR__ M13CST__
100 ÅC416 M16CSB__ M16CSA__ M16CSP__ M16CSO__ M16CSR__ M16CST__
100 ÅdiC410 M10DCB__ M10DCA__ M10DCP__ M10DCO__ M10DCR__ M10DCT__
100 ÅdiC413 M13DCB__ M13DCA__ M13DCP__ M13DCO__ M13DCR__ M13DCT__
100 ÅC81.8 MF1CMD__ MF1CMC__
100 ÅC82.5 MH2CMD__ MH2CMC__ MH2CMA__
100 ÅC83.5 MH3CMD__ MH3CMC__ MH3CMB__ MH3CMA__ MH3CMP__
100 ÅC85 M05CMD__ M05CMC__ M05CMJ__ M05CMB__ M05CMA__ M05CMP__ M05CMO__ M05CMR__ M05CMT__
100 ÅC87 M07CMB__ M07CMA__ M07CMP__ M07CMO__ M07CMR__ M07CMT__
100 ÅC810 M10CMD__ M10CMB__ M10CMA__ M10CMP__ M10CMO__ M10CMR__ M10CMT__
100 ÅC813 M13CMB__ M13CMA__ M13CMP__ M13CMO__ M13CMR__ M13CMT__
100 ÅC816 M16CMB__ M16CMA__ M16CMP__ M16CMO__ M16CMR__ M16CMT__
100 ÅC181.8 MF1CLD__ MF1CLC__
100 ÅC182.5 MH2CLD__ MH2CLC__ MH2CLA__
100 ÅC183.5 MH3CLD__ MH3CLC__ MH3CLB__ MH3CLA__ MH3CLP__
100 ÅC185 M05CLD__ M05CLC__ M05CLJ__ M05CLB__ M05CLA__ M05CLP__ M05CLO__ M05CLR__ M05CLW__
100 ÅC187 M07CLB__ M07CLA__ M07CLP__ M07CLO__ M07CLR__ M07CLT__
100 ÅC1810 M10CLC__ M10CLJ__ M10CLB__ M10CLA__ M10CLP__ M10CLO__ M10CLR__ M10CLT__
100 ÅC1813 M13CLB__ M13CLA__ M13CLP__ M13CLO__ M13CLR__ M13CLT__
100 ÅC1816 M16CLB__ M16CLA__ M16CLP__ M16CLO__ M16CLR__ M16CLT__
100 ÅC18(w)5 M05WLB__ M05WLA__ M05WLP__ M05WLO__ M05WLR__
100 ÅC18(w)10 M10WLA__ M10WLP__ M10WLO__ M10WLR__
100 ÅNH23.5 MH3NHD__ MH3NHC__ MH3NHB__ MH3NHA__ MH3NHP__
100 ÅNH25 M05NHD__ M05NHC__ M05NHB__ M05NHA__ M05NHP__ M05NHO__ M05NHR__ M05NHT__
100 ÅNH27 M07NHB__ M07NHA__ M07NHP__ M07NHO__ M07NHR__ M07NHT__
100 ÅNH210 M10NHJ__ M10NHB__ M10NHA__ M10NHP__ M10NHO__ M10NHR__ M10NHT__
100 ÅNH213 M13NHB__ M13NHA__ M13NHP__ M13NHO__ M13NHR__ M13NHT__
100 ÅNH216 M16NHB__ M16NHA__ M16NHP__ M16NHO__ M16NHR__ M16NHT__
100 ÅPhenyl5 M05PHD__ M05PHC__ M05PHJ__ M05PHB__ M05PHA__ M05PHP__ M05PHO__ M05PHR__ M05PHT__
100 ÅPhenyl10 M10PHJ__ M10PHB__ M10PHA__ M10PHP__ M10PHO__ M10PHR__ M10PHT__
100 ÅPhenyl16 M16PHB__ M16PHA__ M16PHP__ M16PHO__ M16PHR__ M16PHT__
100 ÅPhenylHexyl10 M10PXA__ M10PXP__ M10PXO__ M10PXR__ M10PXT__
100 ÅPhenylHexyl13 M13PXA__ M13PXP__ M13PXO__ M13PXR__ M13PXT__
300 ÅSIL5 L05SID__ L05SIC__ L05SIB__ L05SIA__ L05SIP__ L05SIO__ L05SIR__
300 ÅSIL10 L10SIB__ L10SIA__ L10SIP__ L10SIO__
300 ÅSIL16 L16SIB__ L16SIA__ L16SIP__ L16SIO__
300 ÅC45 L05CSD__ L05CSC__ L05CSB__ L05CSA__ L05CSP__ L05CSO__
300 ÅC410 L10CSB__ L10CSA__ L10CSP__ L10CSO__ L10CSR__ L10CST__
300 ÅC416 L16CSB__ L16CSA__ L16CSP__ L16CSO__ L16CST__
300 ÅdiC410 L10DCB__ L10DCA__ L10DCP__ L10DCO__
300 ÅdiC416 L16DCB__ L16DCA__ L16DCP__ L16DCO__ L16DCR__ L16DCT__
300 ÅC85 L05CMD__ L05CMC__ L05CMB__ L05CMA__ L05CMP__ L05CMO__
300 ÅC810 L10CMB__ L10CMA__ L10CMP__ L10CMO__ L10CMR__ L10CMT__
300 ÅC816 L16CMB__ L16CMA__ L16CMP__ L16CMO__
300 ÅC185 L05CLD__ L05CLC__ L05CLB__ L05CLA__ L05CLP__ L05CLO__
300 ÅC1810 L10CLB__ L10CLA__ L10CLP__ L10CLO__ L10CLR__ L10CLT__
300 ÅC1816 L16CLB__ L16CLA__ L16CLP__ L16CLO__ L16CLR__
ClassicShellC82.5 NH2CMD__ NH2CMA__
EternityC182.5 EH2CLD__ EH2CLC__ EH2CLA__
EternityC185 E05CLD__ E05CLC__ E05CLB__ E05CLA__ E05CLP__ E05CLO__ E05CLR__
EternityPhenylHexyl2.5 EH2PXD__ EH2PXC__ EH2PXA__
EternityPhenylHexyl5 E05PXD__ E05PXC__ E05PXB__ E05PXA__ E05PXP__ E05PXO__ E05PXR__
EternityXTC81.8 XF1CMD__
EternityXTC82.5 XH2CMD__ XH2CMA__
EternityXTC85 X05CMD__ X05CMA__ X05CMP__ X05CMO__ X05CMR__
EternityXTC810 X10CMA__ X10CMP__ X10CMO__ X10CMR__
EternityXTC181.8 XF1CLD__ XF1CLA__
EternityXTC182.5 XH2CLD__ XH2CLA__
EternityXTC185 X05CLD__ X05CLB__ X05CLA__ X05CLP__ X05CLO__ X05CLR__
EternityXTC1810 X10CLB__ X10CLA__ X10CLP__ X10CLO__ X10CLR__
EternityXTPhenylHexyl1.8 XF1PXD__
EternityXTPhenylHexyl2.5 XH2PXD__ XH2PXA__
EternityXTPhenylHexyl5 X05PXD__ X05PXA__ X05PXP__ X05PXO__ X05PXQ__ X05PXR__
EternityShellC182.5 YH2CLD__ YH2CLA__
ChiralAmyCoat3 C03ACA__
ChiralAmyCoat10 C10ACA__
ChiralCelluCoat3 C03CCA__
ChiralCelluCoat5 C05CCA__
ChiralCelluCoat10 C10CCA__
ChiralCelluCoat RP5 C05CRA__
ChiralCelluCoat RP10 C10CRA__
SFCSIL2.5 FH2SIC__ FH2SIA__
SFCSIL5 F05SIC__ F05SIA__ F05SIP__ F05SIO__ F05SIR__
SFCSIL10 F10SIA__ F10SIP__ F10SIO__ F10SIR__
SFCDiol2.5 FH2DIC__ FH2DIA__
SFCDiol5 F05DIC__ F05DIA__ F05DIP__ F05DIO__ F05DIR__
SFCDiol10 F10DIA__ F10DIP__ F10DIO__ F10DIR__
SFCCN2.5 FH2CNC__ FH2CNA__
SFCCN5 F05CNC__ F05CNA__ F05CNP__ F05CNO__ F05CNV__
SFCCN10 F10CNA__ F10CNP__ F10CNO__ F10CNR__
SFC2EP2.5 FH2EPC__ FH2EPA__
SFC2EP5 F05EPC__ F05EPA__ F05EPP__ F05EPO__ F05EPR__
SFC2EP10 F10EPA__ F10EPP__ F10EPO__ F10EPR__
SFCXT2.5 FH2XTC__ FH2XTA__
SFCXT5 F05XTC__ F05XTA__ F05XTP__ F05XTO__ F05XTR__
SFCXT10 F10XTA__ F10XTP__ F10XTO__ F10XTR__

Related

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Kromasil® Classic

Product overview

Kromasil® SFC

Product overview