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Metoprolol

Separation of metoprolol on Kromasil CelluCoat by SFC

chromatogram for c0161
Column:Kromasil 5-CelluCoat 4.6 × 250 mm
Part number:C05CCA25
Eluent:CO2/Ethanol/DEA (85/15/0.1)
Flow rate:3 ml/min
Temperature:40°C
Detection:UV 220 nm
Outlet pressure:150 bar
Results
k’1:1.23
N1:11464
α:2.53
Rs:9.8

Reference

Nouryon application note

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