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Antihistamines

Separation of antihistaminic compounds on Kromasil EternityXT C18. Baseline separation can be better obtained with EternityXT PhenylHexyl!!

  • 1 = doxylamine
    s00203
  • 2 = chlorpheniramine
    s00204
  • 3 = diphenhydramine
    s00205
  • 4 = triprolidine
    s00206
chromatogram for g1096
Column:Kromasil EternityXT-5-C18 4.6 × 150 mm
Part number:X05CLA15
Eluent A:acetonitrile / 10 mM ammonium bicarbonate pH 10.5 [10/90]
Eluent B:acetonitrile [100]
Gradient:0 min 60%, 10 min 69% acetonitrile
Flow rate:1.0 ml/min
Temperature:50 °C
Detection:UV 220 nm

Reference

Nouryon application note

Kromasil columns available with the stationary phase used in this application

Click/touch the dot for the combination of stationary phase and column diameter of your interest to access column length availability and further options.
Column diameters, [mm]
FamilyPhasedp [μm]2.14.04.6102030
EternityXTC185 X05CLD__ X05CLB__ X05CLA__ X05CLP__ X05CLO__ X05CLV__